Description

Cationic arginine- and cysteine-rich peptide isolated from fetal and adult rabbit lung. Inhibitor of ACTH-stimulated corticosterone synthesis in rat adrenal cells in vitro.

SEQUENCE: H-Gly-Ile-Cys-Ala-Cys-Arg-Arg-Arg-Phe-Cys-Pro-Asn-Ser-Glu-Arg-Phe-Ser-Gly-Tyr-Cys-Arg-Val-Asn-Gly-Ala-Arg-Tyr-Val-Arg-Cys-Cys-Ser-Arg-Arg-OH (trifluoroacetate salt)
(Cys3 and 31 bridge, Cys5 and 20 bridge, Cys10 and 30 bridge)

ONE-LETTER SEQUENCE: GICACRRRFCPNSERFSGYCRVNGARYVRCCSRR (C3&C31 bridge,C5&C20 bridge,C10&C30 bridge)

MOLECULAR FORMULA: C₁₆₃H₂₅₉N₆₃O₄₄S₆

MOLECULAR WEIGHT: 3997.7

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [88402-03-3]

SYNONYMS:

RESEARCH AREA: Hormonal

REFERENCES:
Q. Zhu et al., Proc. Natl. Acad. Sci. USA , 85, 592 (1988)

SKU(s): ACTH-015A

KEYWORDS: hormone