Description

Amyloid fragment shown to produce both the neurotoxic and the neurotrophic effects of beta-amyloid protein on cultured neurons. Furthermore, the peptide forms aggregates and typical amyloid fibrils resembling those of the beta-amyloid protein in senile plaque cores.

SEQUENCE: H-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: EDVGSNKGAIIGLM

MOLECULAR FORMULA: C₅₉H₁₀₂N₁₆O₂₁S₁

MOLECULAR WEIGHT: 1403.6

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: 144189-71-9

SYNONYMS: Amyloid β-Protein (22-35)

RESEARCH AREA: Alzheimer’s Disease

REFERENCES:
T. Takadera et al., Neurosci. Letters, 161, 41 (1993)

SKU(s): AMYD-019A, AMYD-019B

KEYWORDS: