Description

Peptide substrate that corresponds to the Met/Val substitution of the amyloid precursor protein (APP) beta-secretase cleavage site and used for assaying beta-secretase activity though incapable of detecting cleavage by the endogenous beta-secretase.

SEQUENCE: H-Ser-Glu-Val-Lys-Val-Asp-Ala-Glu-Phe-Arg-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: SEVKVDAEFR

MOLECULAR FORMULA: C₅₁H₈₂N₁₄O₁₈

MOLECULAR WEIGHT: 1179.3

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [252256-43-2 ]

SYNONYMS:

RESEARCH AREA: Alzheimer’s Disease

REFERENCES:
M. Citron et al., Neuron, 14, 661 (1995)
R. Vasser et al., Science, 286, 735 (1999)

SKU(s): AMYD-115A, AMYD-115B

KEYWORDS: