Description

Inhibitor of gamma-secretase, a protease, and believed to aid in the prevention of Alzheimer’s disease. It additionally cleaves the amyloid precursor protein (APP), a enzyme.

SEQUENCE: Z-Leu-Leu-Nle-CHO

ONE-LETTER SEQUENCE: Z-LL-Nle-CHO

MOLECULAR FORMULA: C₂₆H₄₁N₃O₅

MOLECULAR WEIGHT: 475.62

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [133407-83-7]

SYNONYMS: gamma-Secretase Inhibitor I

RESEARCH AREA: Alzheimer’s Disease

REFERENCES:
T. Hartmann et al., Nature Med., 3, 1016 (1997)

SKU(s): AMYD-117A

KEYWORDS: aldehyde (CHO)