Description

Potent and selective Ang-(1-7) inhibitor that antagonizes several actions of Ang-(1-7), including its antidiurectic effect and the changes in MAP produced by Ang-(1-7) microinjection into the dorsomedial or ventrolateral medulla.

SEQUENCE: H-Asp-Arg-Val-Tyr-Ile-His-DAla-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: DRVYIHa

MOLECULAR FORMULA: C₃₉H₆₀N₁₂O₁₁

MOLECULAR WEIGHT: 872.98

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [159432-28-7]

SYNONYMS: A779, (D-Ala⁷)-Angiotensin I/II (1-7)

RESEARCH AREA: Cardiovascular

CITATIONS:
Aravena, Javier et al. International Journal of Molecular Sciences 21, no. 3 (2020): 1167.?
Lu, Yen‐Yu, et al. European Journal of Clinical Investigation 48.1 (2018): e12854.?
Ábrigo, Johanna, et al. Cellular Physiology and Biochemistry 40.1-2 (2016): 27-38.?
Cisternas, Franco, et al. Clinical Science 128.5 (2015): 307-319.?
Morales, María Gabriela, et al. Clinical Science 129.6 (2015): 461-476.?
Brandan, Enrique. Thesis (2015).?

REFERENCES:
Cardiovascular actions of angiotensin-(1-7) Ferreira AJ and Santos RAS, Brazilian Journal of Medical and Biological Research 38(4), 499-507, (2005)

SKU(s): ANGT-009A

KEYWORDS: hormone