Description

This highly cationic peptide was derived from porcine myeloid cells, and forms a typical amphipathic structure compared to other antibacterial peptides. PMAP-23 shows antibacterial activity against Gram positive and negative strains but no human erythrocyte lysis activity.

SEQUENCE: H-Arg-Ile-Ile-Asp-Leu-leu-Trp-Arg-Val-Arg-Arg-Pro-Gln-Lys-Pro-Lys-Phe-Val-Thr-Val-Trp-Val-Arg-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: RIIDLLWRVRRPQKPKFVTVWVR

MOLECULAR FORMULA: C₁₄₀H₂₂₉N₄₃O₂₈

MOLECULAR WEIGHT: 2962.6

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER:

SYNONYMS:

RESEARCH AREA: Antimicrobial

REFERENCES:
M. Zanetti, P. Storici, A. Tossi, M. Scocchi, R. Gennaro, J. Biol. Chem. 269 (1994) 7855?7858.
Guerreiro, Catarina IPD, et al. Protein expression and purification 59.1 (2008): 161-168.

SKU(s): ATMP-012A

KEYWORDS: