[Lys(Me1)373]-p53 (368-393), p53 K373(Me1), biotin-labeled, human
Product Number:
Price range: $138.60 through $390.50
Sequence:
Biotin-Lys-Gly-Trp-His-Leu-Lys-Ser-Lys(Me1)-Lys-Gly-Gln-Ser-Thr-Ser-Arg-His-Lys-Lys-Leu-Met-Phe-Lys-Thr-Glu-Gly-Pro-Asp-Ser-Asp-NH2 (trifluoroacetate salt)
Description
This is human tumor suppressor protein p53 (368-393) monomethylated at Lys373 and biotinylated through a KGW linker at its N-terminus. Methylation at Lys373 is catalyzed by G9a and Glp lysine methyltransferases and is associated with inactive p53.
SEQUENCE: Biotin-Lys-Gly-Trp-His-Leu-Lys-Ser-Lys(Me1)-Lys-Gly-Gln-Ser-Thr-Ser-Arg-His-Lys-Lys-Leu-Met-Phe-Lys-Thr-Glu-Gly-Pro-Asp-Ser-Asp-NH2 (trifluoroacetate salt)
ONE-LETTER SEQUENCE: Biotin-KGWHLKS-K(Me1)-KGQSTSRHKKLMFKTEGPDSD-NH2
MOLECULAR FORMULA:
MOLECULAR WEIGHT: 3582.2
STORAGE CONDITIONS: -20 ± 5 °C
CAS REGISTRY NUMBER:
SYNONYMS:
RESEARCH AREA: Cancer
REFERENCES:
Krishnan, S. et al. ChemBioChem 12, 254 (2011)
Huang, J. et al. J Biol Chem 285, 9636 (2010)
SKU(s): CANC-009A, CANC-009B
KEYWORDS:
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