Description

Irreversible inhibitor of caspase-1 (ICE) that has also been shown to be a potent therapeutic agent against in vivo liver apoptosis in mice.

SEQUENCE: Ac-Tyr-Val-Ala-Asp-CMK

ONE-LETTER SEQUENCE: Ac-YVAD-CMK

MOLECULAR FORMULA: C₂₄H₃₃N₄O₈Cl₁

MOLECULAR WEIGHT: 541

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [178603-78-6]

SYNONYMS:

RESEARCH AREA: Apoptosis

REFERENCES:
J. B. Schulz et al., J Neurosci, 16, 4696 (1996)
N.P.C. Walker et al., Cell 78, 343 (1994)

SKU(s): CASP-012A, CASP-012B

KEYWORDS: