Description

Specific substrate for the determination of caspase-1 and caspase-1-like enzyme activities. Cleavage of this peptide substrate at the P1 Asp residue causes a continuous fluorescent assay, thus useful both in FACS and fluorescence microscopy experiments. Caspase-3 is only weakly active on this substrate.

SEQUENCE: FITC-C6-Tyr-Val-Ala-Asp-Ala-Pro-Lys(DNP)-OH

ONE-LETTER SEQUENCE: FITC-C6-YVADAP-Lys(Dnp)

MOLECULAR FORMULA: C₆₈H₇₈N₁₂O₂₁S₁

MOLECULAR WEIGHT: 1431.48

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER:

SYNONYMS:

RESEARCH AREA: Apoptosis

REFERENCES:
H.J. Korting et al., Virologie, 28, 41 (1977)
A. Chersi et al., Biochim. Biophys. Acta, 1034, 333 (1990)

SKU(s): CASP-037A, CASP-037B

KEYWORDS: dye-labeled, FRET Substrate