Description

Sensitive fluorescent substrate for the assay of caspase-3 activity. When halogen substituents are present, membrane permeability rises.

SEQUENCE: Ac-Asp-Glu-Val-Asp-AFC

ONE-LETTER SEQUENCE: Ac-DEVD-AFC

MOLECULAR FORMULA: C₃₀H₃₄F₃N₅O₁₃

MOLECULAR WEIGHT: 729.6

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [201608-14-2]

SYNONYMS:

RESEARCH AREA: Apoptosis

REFERENCES:
J. Xiang et al., Proc. Natl. Acad. Sci. USA, 93, 14559 (1996)
H.Ohnimus, Personal communication (1997)
J. Sun et al., Biochem. Biophys. Res. Commun., 238, 920 (1997)

SKU(s): CASP-048A, CASP-048B

KEYWORDS: dye-labeled