Description

Designed substrate based on the tetrapeptide-AMC motif that has been used successfully with caspase-1, using the poly (ADP ribose) polymerase cleavage site P1-P4 tetrapeptide.

SEQUENCE: Ac-Asp-Glu-Val-Asp-AMC

ONE-LETTER SEQUENCE: Ac-DEVD-AMC

MOLECULAR FORMULA: C₃₀H₃₇N₅O₁₃

MOLECULAR WEIGHT: 675.65

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [169332-61-0]

SYNONYMS: Caspase 3 (Apopain) Substrate, Caspase 3 Apopain Substrate

RESEARCH AREA: Apoptosis

REFERENCES:
D.W. Nicholson, Nature, 376 (1995)
J. Xiang et al., Proc. Natl. Acad. Sci. USA, 93, 14559 (1996)

SKU(s): CASP-049A, CASP-049B

KEYWORDS: dye-labeled