Description

Fluorogenic substrate that corresponds to one of the cleavage sites of the inactive 32 kD caspase-3 precursor (amino acids 172-175). Substrate for granzyme B.

SEQUENCE: Z-Ile-Glu-Thr-Asp-AFC

ONE-LETTER SEQUENCE: Z-IETD-AFC

MOLECULAR FORMULA: C₃₇H₄₂N₅O₁₃F₃

MOLECULAR WEIGHT: 821.8

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [219138-02-0]

SYNONYMS:

RESEARCH AREA: Apoptosis

REFERENCES:
Z. Han et al., J. Biol. Chem., 272, 13432 (1997)

SKU(s): CASP-064A, CASP-064B

KEYWORDS: dye-labeled