Description
Highly sensitive, photostable fluorogenic substrate for the determination of intracellular caspase-3 activity. The fluorophore rhodamine 110(Rh110) can be observed at an emission wavelength fo 535 nm with an excitation wavelength of 485 nm. With (H-Asp-Glu-Val-Asp)2-Rhodamine 110 (M-2620) the fluorescence intensity can be measured by flow cytometry, microwell plate reader, or fluorescence microscopy.
SEQUENCE: (Z-Asp-Glu-Val-Asp)2-R110
ONE-LETTER SEQUENCE: (Z-DEVD)2-R110
MOLECULAR FORMULA: C72H78N10O27
MOLECULAR WEIGHT: 1515.44
STORAGE CONDITIONS: -20 ± 5 °C
CAS REGISTRY NUMBER: [223538-61-2]
SYNONYMS: (Z-Asp-Glu-Val-Asp)₂-Rhodamine 110
RESEARCH AREA: Apoptosis
CATEGORY: Apoptosis Related Peptides »
REFERENCES:
Science 281, 1312 (1998)
J. Biol. Chem., 276, 6974 (2001)
Biochemistry 38, 13906 (1999)
PRODUCT CITATIONS:
González, Gu, Linlin, et al. Cell Death & Differentiation (2021): 1-15. »
SKU(s): CASP-066A, CASP-066B, CASP-066C, CASP-066D
KEYWORDS: dye-labeled