Description

Ac-AAVALLPAVLLALLAP-IETD-CHO is a composite of two peptide sequences, reversible caspase-8 inhibitor (Ac-IETD-CHO, CASP-057) and hydrophobic CCP signal peptide for Kaposi fibroblast growth factor (K-FGF).

SEQUENCE: Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-CHO

ONE-LETTER SEQUENCE: Ac-AAVALLPAVLLALLAPIETD-CHO

MOLECULAR FORMULA: C₉₅H₁₆₂N₂₀O₂₆

MOLECULAR WEIGHT: 2000.5

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [886462-83-5]

SYNONYMS: Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-aldehyde, acetyl-AAVALLPAVLLALLAP-IETD-CHO, p-IETD-CHO, Ac-AAVALLPAVLLALLAP-IETD-CHO

RESEARCH AREA: Apoptosis

REFERENCES:
Lin, Yao-Zhong, et al. Journal of Biological Chemistry 270.24 (1995): 14255-14258. (original)
Liang, Ye, Chaohua Yan, and Nina F. Schor. Oncogene 20.45 (2001): 6570.
Wondrak, Georg T. Free Radical Biology and Medicine 43.2 (2007): 178-190.
Satou, Motoyasu, et al. Endocrinology 151.10 (2010): 4765-4775.
Qiao, Shuxi, et al. Biochemical Pharmacology 83.9 (2012): 1229-1240.

SKU(s): CASP-075A, CASP-075B

KEYWORDS: aldehyde (CHO)