Description

This peptide derived from the vasopressin-neurophysin 2-copeptin precursor, a prognostic marker in a variety of diseases, such as sepsis, community-acquired pneumonia, chronic obstructive pulmonary failure, heart failure and myocardial infarction.

SEQUENCE: H-Ala-Ser-Asp-Arg-Ser-Asn-Ala-Thr-Gln-Leu-Asp-Gly-Pro-Ala-Gly-Ala-Leu-Leu-Leu-Arg-Leu-Val-Gln-Leu-Ala-Gly-Ala-Pro-Glu-Pro-Phe-Glu-Pro-Ala-Gln-Pro-Asp-Ala-Tyr-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: ASDRSNATQLDGPAGALLLRLVQLAGAPEPFEPAQPDAY

MOLECULAR FORMULA: C₁₇₇H₂₇₉N₄₉O₅₈

MOLECULAR WEIGHT: 4021.46

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [78362-34-2]

SYNONYMS:

RESEARCH AREA: Cardiovascular

REFERENCES:
J.Struck et al., Peptides, 26, 2500 (2005)
N.G.Morgenthaler et al., Clin. Chem., 52, 112 (2006)
S.Q.Khan et al., Circulation, 115, 2103 (2007)
G.Szinnai et al., J. Clin. Endocrinol. Metab., 92, 3973 (2007)
M.Katan et al., Crit. Care, 12, 117 (2008)
R.Seligman et al., Crit. Care, 12, R11 (2008)

SKU(s): COPE-001A, COPE-001B

KEYWORDS: