Description

CRP, an acute-phase serum protein synthesized in response to inflammatory cytokines, produces antitumor effects in animals. CRP174-185 induces the circulation of soluble IL-6 receptor (sIL-6R) and modulates chemotaxis.

SEQUENCE: H-Ile-Tyr-Leu-Gly-Gly-Pro-Phe-Ser-Pro-Asn-Val-Leu-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: IYLGGPFSPNVL

MOLECULAR FORMULA: C₆₂H₉₃N₁₃O₁₆

MOLECULAR WEIGHT: 1276.5

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [160369-86-8]

SYNONYMS:

RESEARCH AREA: Cancer

REFERENCES:

B.P.Barna et al., Cancer Immunol. Immunother., 36, 171 (1993)

M.J.Thomassen et al., J. Immunother., 13, 1 (1993)

B.P.Barna et al., Cancer Immunol. Immunother., 38, 38 (1994)

SKU(s): CRP-002A, CRP-002B

KEYWORDS: hormone