Description

beta-Lipotropin (61-91), secreted by the pituitary gland, is the most potent of the opiate peptides and is more effective than morphine in tests of opiate receptor binding, analgesia and catatonia. High doses of beta-endorphin may cause rigidity and hypothermia in rats.

SEQUENCE: H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu-OH

ONE-LETTER SEQUENCE: YGGFMTSEKSQTPLVTLFKNAIIKNAYKKGE

MOLECULAR FORMULA: C₁₅₈H₂₅₁N₃₉O₄₆S₁

MOLECULAR WEIGHT: 3465.1

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [61214-51-5]

SYNONYMS:

RESEARCH AREA: Pain

REFERENCES:
C.H. Li et al., JMC, 20, 325 (1977)

SKU(s): ENDP-001A

KEYWORDS: