Description

SPARC is a transiently expressed extracellular matrix-binding protein that alters cell shape and regulates endothelial cell proliferation in vitro. KGHK , a copper-binding peptide fragment, has been shown to be a potent stimulator of angiogenesis. Specific degradation of SPARC by proteases of the extracellular fluid may release this bioactive peptide.

SEQUENCE: H-Lys-Gly-His-Lys-OH (acetate salt)

ONE-LETTER SEQUENCE: KGHK

MOLECULAR FORMULA: C₂₀H₃₆N₈O₅

MOLECULAR WEIGHT: 468.56

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [155149-79-4]

SYNONYMS: SPARC Fragment 119-122 Mouse

RESEARCH AREA: Miscellaneous

REFERENCES:
T.F.Lane et al., J. Cell Biol., 125, 929 (1994)

SKU(s): GRFF-009A, GRFF-009B

KEYWORDS: