Description

Uroguanylin is secreted by enterochromaffin cells in the duodenum and proximal small intestine. The peptide is involved in appetite and perceptions of ‘fullness’ after eating meals.

SEQUENCE: H-Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu-OH

(Cys4 and 12 bridge, Cys7 and 15 bridge)

ONE-LETTER SEQUENCE: NDDCELCVNVACTGCL (C4&C12 bridge, C7&C15 bridge)

MOLECULAR FORMULA: C₆₄H₁₀₂N₁₈O₂₆S₄

MOLECULAR WEIGHT: 1667.88

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [152175-68-3]

SYNONYMS: Uroguanylin Topoisomer A (human), UGN Topoisomer A (human)

RESEARCH AREA: Gastrointestinal

REFERENCES:

T. Kita et al., Am. J. Physiol., 266, F342 (1994)

Rahbi H, Narayan H, Jones DJ, Ng LL. “The uroguanylin system and human disease”. Clinical Science. 123,12 (2012)

SKU(s): GUAN-003A, GUAN-003B

KEYWORDS: