Description

This peptide is the fluorogenic substrate for assaying histone deacetylase (HDAC) activity in a two-step enzymatic reaction. The assay consists of the initial lysine deacetylation by HDAC followed by the release of the fluorescent group by trypsin.

SEQUENCE: Ac-Arg-Gly-Lys(Ac)-AMC (trifluoroacetate salt)

ONE-LETTER SEQUENCE: Ac-RGK(Ac)-AMC

MOLECULAR FORMULA: C₂₈H₄₀N₈O₇

MOLECULAR WEIGHT: 600.68

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [660846-97-9]

SYNONYMS: Histone deacetylase, HDAC substrate

RESEARCH AREA: Miscellaneous

REFERENCES:
D.Wegener et al., Chem. Biol., 10, 61 (2003)

SKU(s): HIST-006A, HIST-006B

KEYWORDS: dye-labeled