Description

Phosphorylation at histone H1 Ser42 occurs only after phosphorylation at Thr34, Thr46, or Thr53 in vivo. This peptide is histone H1 (29-59) phosphorylated at Ser42. Histone H1 phosphorylation is associated with chromosome condensation and transcriptional regulation.

SEQUENCE: H-Lys-Asp-Thr-Lys-Pro-Thr-Pro-Thr-Lys-Gly-Lys-Ala-Ala-Ser(PO3H2)-Ala-Ser-Thr-Thr-Pro-Val-Lys-Lys-Asp-Val-Thr-Pro-Val-Lys-Ala-Asp-Thr-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: KDTKPTPTKGKAA-pS-ASTTPVKKDVTPVKADT

MOLECULAR FORMULA:

MOLECULAR WEIGHT: 3249.6

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER:

SYNONYMS:

RESEARCH AREA: Miscellaneous

REFERENCES:
Garcia, B. et al. Mol Cell Proteomics 5, 1593 (2006)
Dou, Y. and MA. Gorovsky Mol Cell 6, 225 (2000)
Mizzen, C. et al. J Biol Chem 274, 14533 (1999)
Swank, R. et al. Biochem 36, 13761 (1997)

SKU(s): HIST-009A, HIST-009B

KEYWORDS: phosphorylated