Description

Substrate that can be cleaved by the HIV-1 protease at the Tyr-Pro position, thus resulting in a time-dependent increase in the intensity of fluorescence.

SEQUENCE: DABCYL-gamma-Abu-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS (trifluoroacetate salt)

ONE-LETTER SEQUENCE: DABCYL-gamma-Abu-SQNYPIVQ-EDANS

MOLECULAR FORMULA: C₇₃H₉₇N₁₇O₁₈S₁

MOLECULAR WEIGHT: 1532.74

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [127134-13-8]

SYNONYMS: DABCYL-Gaba-SQNYPIVQ-EDANS, DABCYL-γ-Abu-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS

RESEARCH AREA: Antimicrobial

REFERENCES:
E.D. Matayoshi et al., Science, 247, 954 (1990)
L.Bannwarth et al., J. Med. Chem., 49, 4657 (2006)
M.W. Pennington et al., Peptides, Proceedings of the 22nd European Peptide Symposium Interlaken, Switzerland, P. 936, (1992)
C.H. Schneider and A.N. Eberle, eds., Escom, Leiden (1993)

SKU(s): HIV-002A, HIV-002B

KEYWORDS: dye-labeled, FRET Substrate