Description

The octadecapeptide derived from the CD4 attachment region of HIV gp120 inhibited the syncytial formation in vitro. According to immunological studies, the HIV (gp120) fragment 421-438 generated high titres of anti-gp120 antibodies following immunization in mice, rabbits, and goats.

SEQUENCE: H-Lys-Gln-Phe-Ile-Asn-Met-Trp-Gln-Glu-Val-Gly-Lys-Ala-Met-Tyr-Ala-Pro-Pro-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: KQFINMWQEVGKAMYAPP

MOLECULAR FORMULA: C₉₉H₁₄₈N₂₄O₂₅S₂

MOLECULAR WEIGHT: 2138.54

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [129318-38-3]

SYNONYMS:

RESEARCH AREA: Antimicrobial

REFERENCES:
W.J.W.Morrow et al., Immunology, 75, 557 (1992)
R.M.Ferraz et al., J. Mol. Recognit., 22, 255 (2009)

SKU(s): HIV-009A, HIV-009B

KEYWORDS: