Description

Asn-Ala-ICAM 1 (1-21) inhibits virus replication in HIV-1 infected HTLV-1 transformed cells (MT-2 cells). The peptide induces up to 70% inhibition of reverse transcriptase activity, up to 60% reduction of soluble virus antigen production, and inhibition of syncytium formation.

SEQUENCE: H-Asn-Ala-Gln-Thr-Ser-Val-Ser-Pro-Ser-Lys-Val-Ile-Leu-Pro-Arg-Gly-Gly-Ser-Val-Leu-Val-Thr-Cys-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: NAQTSVSPSKVILPRGGSVLVTC

MOLECULAR FORMULA: C₉₉H₁₇₃N₂₉O₃₂S₁

MOLECULAR WEIGHT: 2313.72

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [139227-42-2]

SYNONYMS:

RESEARCH AREA: Antimicrobial

REFERENCES:
J.V.Fecondo et al., AIDS Res. Human Retroviruses, 9, 733 (1993)

SKU(s): HIV-022A, HIV-022B

KEYWORDS: