Description

Human T lymphotropic virus type 1 HTLV-1 Tax (11-19) is an immunodominant HLA-A2-restricted epitope. It is recognized by a high number of CD8+ cytotoxic T lymphocytes (CTLs) in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), a demyelinating inflammatory neurologic disease associated with HTLV-1 infection. H-6096 therefore represents a useful tool to elucidate the role of antigen-specific CD8+ CTLs in HAM/TSP.

SEQUENCE: H-Leu-Leu-Phe-Gly-Tyr-Pro-Val-Tyr-Val-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: LLFGYPVYV

MOLECULAR FORMULA: C₅₆H₇₉N₉O₁₂

MOLECULAR WEIGHT: 1070.3

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [141677-18-1]

SYNONYMS:

RESEARCH AREA: Antimicrobial

REFERENCES:
T.F.Greten et al., Proc. Natl. Acad. Sci. USA, 95, 7568 (1998)
U.Tomaru et al., Nat. Med., 9, 469 (2003)

SKU(s): HTLV-001A, HTLV-001B

KEYWORDS: