Description

KGF receptor peptide, which corresponds to residues 199-223 of the KGF receptor alternative exon, blocks the mitogenic activity of KGF and the interaction between KGF and its receptor. The peptide binds directly and specifically to KGF and thus represents a critical part of the KGF receptor ligand binding site.

SEQUENCE: H-His-Ser-Gly-Ile-Asn-Ser-Ser-Asn-Ala-Glu-Val-Leu-Ala-Leu-Phe-Asn-Val-Thr-Glu-Met-Asp-Ala-Gly-Glu-Tyr-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: HSGINSSNAEVLALFNVTEMDAGEY

MOLECULAR FORMULA: C₁₁₄H₁₇₄N₃₀O₄₂S₁

MOLECULAR WEIGHT: 2668.88

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [161338-76-7]

SYNONYMS:

RESEARCH AREA: Cancer

REFERENCES:
D.P.Bottaro et al., J. Biol. Chem., 268, 9180 (1993)

SKU(s): KGF-001A, KGF-001B

KEYWORDS: