Description

Peptide derived from domain III of the laminin B1 chain represents minimal sequence necessary for cell attachment and laminin receptor-binding activity. It also inhibits lung tumor colony formation in mice injected with melanoma cells. Moreover, this peptide mediates the adhesion of a variety of epithelical cells to laminin.

SEQUENCE: H-Tyr-Ile-Gly-Ser-Arg-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: YIGSR

MOLECULAR FORMULA: C₂₆H₄₂N₈O₈

MOLECULAR WEIGHT: 594.7

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [110590-64-2]

SYNONYMS: Laminin β-1 Chain (929-933) (human, mouse), YIGSR, Laminin Fragment (929-933)

RESEARCH AREA: Cancer

REFERENCES:
G.Hunt, Exp. Cell Biol., 57, 165 (1989)
Y.Iwamoto et al., J. Cell. Physiol., 134, 287 (1988)
Y.Iwamoto et al., Science, 238, 1132 (1987)
J.Graf et al., Biochemistry, 26, 6896 (1987)

SKU(s): LAMN-002A

KEYWORDS: