Description

Biotinylated NAD+ (6-biotin-17-nicotinamide-adenine-dinucleotide, 6-biotin-17-NAD), is a non-radiolabeled substrate alternative for measuring the activity of poly (ADP-ribose) polymerase (PARP). PARPs are a family of enzymes primarily involved in cellular processes such as programmed cell death and DNA repair. NAD+ is a required substrate for generating ADP-ribose monomers. A biotinylated variant of NAD+ enables the indirect measurement of PARP activity through detection of biotin incorporation using a conjugated-streptavidin detection system.

SEQUENCE: (6-biotin-17-nicotinamide-adenine-dinucleotide)

ONE-LETTER SEQUENCE:

MOLECULAR FORMULA: C₄₅H₆₇N₁₂O₁₈P₂S

MOLECULAR WEIGHT: 1158.1

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER:

SYNONYMS:

RESEARCH AREA: Apoptosis

REFERENCES:
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SKU(s): LINK-002A

KEYWORDS: