Description

KR-12 corresponds to amino acid residues 18-29 of LL-37 and is the smallest peptide of LL-37 retaining antibacterial activity. KR-12 displays a selective toxic effect on bacteria but not on human cells. It may be used as a template for developing novel antimicrobial agents of therapeutic use.

SEQUENCE: H-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-NH2

ONE-LETTER SEQUENCE: KRIVQRIKDFLR-NH2

MOLECULAR FORMULA: C₇₁H₁₂₇N₂₅O₁₅

MOLECULAR WEIGHT: 1570.95

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [1218951-51-9]

SYNONYMS: Antibacterial Protein LL-37 amide (human) (18-29), LL-37 (18-29), LL37 (18-29), CAMP (18-29), KR-12 amide

RESEARCH AREA: Antimicrobial

REFERENCES:
G.Wang, J. Biol. Chem., 283, 32637 (2008)

SKU(s): LL37-001A, LL37-001B, LL37-001C

KEYWORDS: