Description

Melan A corresponds to residues 27-35 of the nonmutated melanoma-associated antigen MART-1/Melan A. The sequence AAGIGILTV is the immunodominant epitope recognized by most melanoma-specific, HLA-A*0201-restricted, cytotoxic T lymphocytes (CTL).

SEQUENCE: H-Ala-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val-OH (acetate salt)

ONE-LETTER SEQUENCE: AAGIGILTV

MOLECULAR FORMULA: C₃₇H₆₇N₉O₁₁

MOLECULAR WEIGHT: 813.99

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [156251-11-5]

SYNONYMS:

RESEARCH AREA: Cancer

REFERENCES:
A.van Elsas et al., Eur. J. Immunol., 26, 1683 (1996)
M.J.Mäurer et al., Eur. J. Immunol., 26, 2613 (1996)
J.N.Cormier et al., Cancer J. Sci. Am., 3, 37 (1997)
F.O.Nestle et al., Nat. Med., 4, 328 (1998)
M.P.Velders et al., Crit. Rev. Immunol., 18, 7 (1998)

SKU(s): MART-002A, MART-002B

KEYWORDS: