Description

This peptide is the immunodominant eptitope of Myelin Basic Protein, which has been shown to induce the proliferation of an encephalitogenic, myelin basic protein-specific T cell line. Active immunization of rats with this peptide induced acute experimental autoimmune encephalomyelitis. This protein region is highly conserved among mammalian species.

SEQUENCE: H-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: VHFFKNIVTPRTP

MOLECULAR FORMULA: C₇₄H₁₁₄N₂₀O₁₇

MOLECULAR WEIGHT: 1555.84

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [118506-26-6]

SYNONYMS:

RESEARCH AREA: Multiple Sclerosis

REFERENCES:
R.E.Jones et al., J. Neuroimmunol., 37, 203 (1992)

SKU(s): MBP-001A, MBP-001B

KEYWORDS: