Description

This myelin basic protein analog reversed established paralysis induced in mice by transfer of a T-cell clone recognizing the myelin basic protein epitope (87-99). This altered peptide ligand caused regression of the inflammatory infiltrates and disappearance of the heterogenous T-cell infiltrates from the brain.

SEQUENCE: H-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Ala-Arg-Thr-Pro-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: VHFFKNIVTARTP

MOLECULAR FORMULA: C₇₂H₁₁₂N₂₀O₁₇

MOLECULAR WEIGHT: 1529.81

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER:

SYNONYMS:

RESEARCH AREA: Multiple Sclerosis

REFERENCES:
S.Brocke et al., Nature, 379, 343 (1996)

SKU(s): MBP-002A, MBP-002B

KEYWORDS: