Description

MCD Peptide HR-1 is isolated from the venom of the giant hornet Vespa Orientalis and differs structurally from the MCD peptide from honeybee venom but possesses similar biological effects. These peptides are capable of degranulating rat mast cells, thereby initiating histamine release.

SEQUENCE: H-Phe-Leu-Pro-Leu-Ile-Leu-Gly-Lys-Leu-Val-Lys-Gly-Leu-Leu-NH2 (trifluoroacetate salt)

ONE-LETTER SEQUENCE: FLPLILGKLVKGLL-NH2

MOLECULAR FORMULA: C₇₇H₁₃₅N₁₇O₁₄

MOLECULAR WEIGHT: 1523.03

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [80388-04-1]

SYNONYMS: Mast Cell Degranulating (MCD) Peptide HR-2

RESEARCH AREA: Inflammation

REFERENCES:
M.U. Tuichibaev et al., Biochem. USSR, 53, 183 (1988)

SKU(s): MCDP-002A, MCDP-002B

KEYWORDS: