Description

This peptide is the C-terminally amidated octapeptide found in bovine brain and adrenal tissue, corresponds to residues 206-213 of the bovine proenkephalin precursor. It is also related in sequence to the bovine adrenal medulla peptides. So far, it is the only endogenous opioid peptide with high affinity for ? opioid receptors.

SEQUENCE: H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-NH2 (trifluoroacetate salt)

ONE-LETTER SEQUENCE: YGGFMRRV-NH2

MOLECULAR FORMULA: C₄₄H₆₉N₁₅O₉S₁

MOLECULAR WEIGHT: 984.19

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [88377-68-8]

SYNONYMS:

RESEARCH AREA: Pain

REFERENCES:
H.Matsuo et al., Nature, 305, 721 (1983)
E.Weber et al., Proc. Natl. Acad. Sci. USA, 80, 7362 (1983)
P.D.Marley et al., Brain Res., 363, 10 (1986)
M.Sonders and E.Weber, J. Neurochem., 49, 671 (1987)

SKU(s): METO-001A, METO-001B

KEYWORDS: