Description

Best fluorogenic substrate developed for matrilysin (also called punctuated metalloproteinase 1, PUMP-1 or MMP-7) thus far. Besides good kinetic parameters (kcat/km= 1.9 x 10⁵ M^-1s^-1), it presents good solubility in assay buffer.

SEQUENCE: DNP-Arg-Pro-Leu-Ala-Leu-Trp-Arg-Ser-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: DNP-RPLALWRS

MOLECULAR FORMULA: C₅₂H₇₇N₁₇O₁₄

MOLECULAR WEIGHT: 1164.30

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [172666-82-9]

SYNONYMS: MMP-7 Fluorogenic Substrate

RESEARCH AREA: Cancer

REFERENCES:
A.R. Welch, et al., Arch. Biochem. Biophys. 324, 59 (1995)

SKU(s): MMPS-013A, MMPS-013B

KEYWORDS: dye-labeled, FRET Substrate