Description

Efficient substrate for intestitial/vertebrate collagenase (MMP-1), stromelysin (MMP-3), gelatinases (MMP-2 and MMP-9) and the punctuated metalloproteinase (MMP-7).

SEQUENCE: DNP-Pro-Leu-Gly-Leu-Trp-Ala-DArg-NH2 (trifluoroacetate salt)

ONE-LETTER SEQUENCE: Dnp-PLGLWA-DArg-NH2

MOLECULAR FORMULA: C₄₅H₆₄N₁₄O₁₁

MOLECULAR WEIGHT: 977.09

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [121282-17-5]

SYNONYMS: Dnp-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg-NH₂

RESEARCH AREA: Cancer

REFERENCES:
D.M. Bickett, et al., Anal. Biochem. 212, 58 (1993)
C.G. Knight, et al., FEBS Lett. 296, 263 (1992)
K. Darlak, et al., J. Biol. Chem. 265, 5199 (1990)
M.S. Stack, and R.D. Gray, J. Biol. Chem. 264, 4277 (1989)

SKU(s): MMPS-020A, MMPS-020B, MMPS-020C, MMPS-020D

KEYWORDS: dye-labeled, FRET Substrate