Description

This peptide was originally isolated from rat brains which had experienced trauma. This small 13-mer peptide promoted neuronal survival of septal cholinergic neurons and mesencephalic dopaminergic neurons in primary cultures from neonatal rats. Furthermore, it rescued neurons from injury caused by glutamate.

SEQUENCE: H-Glu-Ala-Leu-Glu-Leu-Ala-Arg-Gly-Ala-Ile-Phe-Gln-Ala-NH2 (ammonium salt)

ONE-LETTER SEQUENCE: EALELARGAIFQA-NH2

MOLECULAR FORMULA: C₆₂H₁₀₂N₁₈O₁₈

MOLECULAR WEIGHT: 1387.6

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [148330-12-5]

SYNONYMS:

RESEARCH AREA: Neuropeptides

REFERENCES:
T.Hama et al., FEBS Lett., 396, 143 (1996)

SKU(s): NEUP-016A, NEUP-016B

KEYWORDS: