Description

This peptide is a potent and highly selective antagonist at the delta-opioid receptor (IC50 = 6 nM) and therefore an ideal candidate for the study of opioid pharmacology (delta-opioid receptors).

SEQUENCE: H-Tyr-Tic-Phe-Phe-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: Y-Tic-FF

MOLECULAR FORMULA: C₃₇H₃₈N₄O₆

MOLECULAR WEIGHT: 634.73

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [146369-65-5]

SYNONYMS:

RESEARCH AREA: Pain

REFERENCES:
P.W.Schiller et al., Proc. Natl. Acad. Sci. USA, 89, 11871 (1992)
V.Kumar et al., J. Med. Chem., 43, 5050 (2000)
D.Y.Maeda et al., J. Med. Chem., 43, 5044 (2000)

SKU(s): OPIO-013A, OPIO-014

KEYWORDS: