Description

This peptide is the carboxyl-terminal fragment of pTHrP, which is a potent inhibitor of osteoclastic bone resorption. It is suggested that this product acts directly on osteoclasts.

SEQUENCE: H-Thr-Arg-Ser-Ala-Trp-Leu-Asp-Ser-Gly-Val-Thr-Gly-Ser-Gly-Leu-Glu-Gly-Asp-His-Leu-Ser-Asp-Thr-Ser-Thr-Thr-Ser-Leu-Glu-Leu-Asp-Ser-Arg-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: TRSAWLDSGVTGSGLEGDHLSDTSTTSLELDSR

MOLECULAR FORMULA: C₁₄₂H₂₂₈N₄₂O₅₈

MOLECULAR WEIGHT: 3451.62

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [137348-10-8]

SYNONYMS:

RESEARCH AREA: Osteoporosis

REFERENCES:
A.J.Fenton et al., Endocrinology, 129, 1762 (1991)
A.J.Fenton et al., Endocrinology, 129, 3424 (1991)

SKU(s): OSTP-008A, OSTP-008B

KEYWORDS: