Description

pTHrP (107-139) stimulates IL-6 expression in human osteoblastic cells. It inhibits bone resorption in vivo

SEQUENCE: H-Thr-Arg-Ser-Ala-Trp-Leu-Asp-Ser-Gly-Val-Thr-Gly-Ser-Gly-Leu-Glu-Gly-Asp-His-Leu-Ser-Asp-Thr-Ser-Thr-Thr-Ser-Leu-Glu-Leu-Asp-Ser-Arg-NH2
(trifluoroacetate salt)

ONE-LETTER SEQUENCE: TRSAWLDSGVTGSGLEGDHLSDTSTTSLELDSR-NH2

MOLECULAR FORMULA: C₁₄₂H₂₂₉N₄₃O₅₇

MOLECULAR WEIGHT: 3450.64

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [204383-55-1]

SYNONYMS:

RESEARCH AREA: Osteoporosis

REFERENCES:
A.J.Fenton et al., Endocrinology, 129, 1762 (1991)
A.J.Fenton et al., Endocrinology, 129, 3424 (1991)
J.Cornish et al., Endocrinology, 138, 1299 (1997)
F.de Miguel et al., J. Am. Soc. Nephrol., 10, 796 (1999)
A.Valín et al., Endocrinology, 142, 2752 (2001)

SKU(s): OSTP-009A, OSTP-009B

KEYWORDS: