Description

CGRP induces elevation of cAMP and cGMP in rat aorta.

SEQUENCE: H-Ser-Cys-Asn-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2 (trifluoroacetate salt)
(Cys2 and 7 bridge)

ONE-LETTER SEQUENCE: SCNTATCVTHRLAGLLSRSGGVVKDNFVPTNVGSEAF-NH2 (Cys2 and 7 bridge)

MOLECULAR FORMULA: C₁₆₂H₂₆₂N₅₀O₅₂S₂

MOLECULAR WEIGHT: 3806.3

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [96827-03-1]

SYNONYMS: CGRP (rat), Calcitonin Gene Related Peptide-1, alpha-CGRP (rat)

RESEARCH AREA: Cardiovascular

REFERENCES:
S.G. Amara, V. Jonas, M.G. Rosenfeld, E.S. Ong and R.M. Evans, Nature, 298, 240 (1982) (Original)
M.G. Rosenfeld, J.J. Mermond, S.G. Amara, L.W. Swanson, P.E. Sawchenko, J. Rivier, W.W. Vale and R.M. Evans, Nature, 304, 129 (1983) (Processing and Distribution in Neural Tissue)

SKU(s): OSTP-023A, OSTP-023B

KEYWORDS: hormone