Description

This peptide is the tethered ligand sequence of mouse PAR-2, which like the thrombin receptor is a protease-activated receptor present in keratinocytes. This peptide was found to be equipotent with SFLLRN in activating keratinocyte inositolphospholipid hydrolysis and calcium mobilization.

SEQUENCE: H-Ser-Leu-Ile-Gly-Arg-Leu-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: SLIGRL

MOLECULAR FORMULA: C₂₉H₅₅N₉O₈

MOLECULAR WEIGHT: 657.81

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [164081-25-8]

SYNONYMS:

RESEARCH AREA: Hematology

REFERENCES:
R.J.Santulli et al., Proc. Natl. Acad. Sci. USA, 92, 9151 (1995)
A. Bhattacharya et al., J. Pharmacol. Exp. Ther., 297, 573 (2001)
B. Al-Ani, et al., J. of Physiol. Pharmacol., 73, 1203 (1995)

SKU(s): PARP-005A, PARP-005B

KEYWORDS: