Description

20-residue peptide that represents the active site of the cAMP-dependent protein kinase inhibitor protein in skeletal muscle, binds to the cAMP-dependent protein kinase with high affinity and competitively inhibits enzyme activity.

SEQUENCE: H-Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: TTYADFIASGRTGRRNAIHD

MOLECULAR FORMULA: C₉₄H₁₄₈N₃₂O₃₁

MOLECULAR WEIGHT: 2222.4

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [99534-03-9]

SYNONYMS: PKI (5-24)

RESEARCH AREA: Protein Kinases and Phosphatases

REFERENCES:
J.D. Scott et al., PNAS, 82, 5732 (1985)
H.C. Cheng et al., Biochem J., 231, 655 (1985)

SKU(s): PKCP-004A

KEYWORDS: