Description

Parathyroid hormone (PTH) regulates the metabolism of calcium and phosphate. PTH and PTH-related polypeptide (PTHrP) play important roles in calcium homeostasis of bone, kidney, breast, and placenta; they signal via the PTH/PTHrP and PTH2 receptors. PTH(1?34) administration suppresses cardiovascular calcification and down-regulates aortic osteogenic programs driven by diabetes and dyslipidemia.

SEQUENCE: Biotin-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: Biotin-SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNF

MOLECULAR FORMULA: C₁₉₁H₃₀₅N₅₇O₅₃S₃

MOLECULAR WEIGHT: 4344.07

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [213779-14-7]

SYNONYMS: Biotinyl-pTH (1-34) (human)

RESEARCH AREA: Osteoporosis

REFERENCES:

SKU(s): PTHP-014A

KEYWORDS: