Description

Cyclic MSH analog is a potent full agonist of the melanocortin-3 and melanocortin-4 receptors (MC3-R and MC4-R). MTII is a useful tool in the study of the agouti obesity syndrome and the role of melanocortinergic neurons in feeding.

SEQUENCE: Ac-Nle-cyclo(Asp-His-DPhe-Arg-Trp-Lys-NH2)
(Peptide beta bond Asp3 and Lys8 bridge)

ONE-LETTER SEQUENCE: Ac-Nle-cyclo(DHfRWK-NH2)
(Peptide beta bond D3 and K8 bridge)

MOLECULAR FORMULA: C₅₀H₆₉N₁₅O₉

MOLECULAR WEIGHT: 1024.19

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [121062-08-6]

SYNONYMS: MTII, Bremelanotide amide, Melanotan II

RESEARCH AREA: Gastrointestinal

REFERENCES:
V.J. Hruby et al., J. Med. Chem., 38, 3435 (1995)

SKU(s): SOMA-003A, SOMA-003B

KEYWORDS: hormone, lactam, peptide macrocycle