Description

Synthesized substrate cleaved specifically at the Ala-Ser bond in order to liberate the C-terminal peptide-EDANS fragment from the proximity quenching effect of the DABCYL group, thus representing the first fluorescence-based assay of the herpes virus proteases and permits the characterization of potential inhibitors.

SEQUENCE: DABCYL-Arg-Gly-Val-Val-Asn-Ala-Ser-Ser-Arg-Leu-Ala-EDANS (trifluoroacetate salt)

ONE-LETTER SEQUENCE: Dabcyl-RGVVNASSRLA-EDANS

MOLECULAR FORMULA: C₇₃H₁₀₉N₂₃O₁₈S₁

MOLECULAR WEIGHT: 1628.9

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [163265-38-1]

SYNONYMS:

RESEARCH AREA: Apoptosis

REFERENCES:
B.P. Holskin et al., Anal. Biochem. , 227, 148 (1995)

SKU(s): SUBS-015A, SUBS-015B

KEYWORDS: dye-labeled, FRET Substrate