Description

As a new member of the CRF family of neuropeptides, this peptide selectively binds to the type 2 CRF receptor (CRF-R2) while exhibiting no appreciable activity on CRF-R1.

SEQUENCE: H-Ile-Val-Leu-Ser-Leu-Asp-Val-Pro-Ile-Gly-Leu-Leu-Gln-Ile-Leu-Leu-Glu-Gln-Ala-Arg-Ala-Arg-Ala-Ala-Arg-Glu-Gln-Ala-Thr-Thr-Asn-Ala-Arg-Ile-Leu-Ala-Arg-Val-Gly-His-Cys-NH2 (trifluoroacetate salt)

ONE-LETTER SEQUENCE: IVLSLDVPIGLLQILLEQARARAAREQATTNARILARVGHC-NH2

MOLECULAR FORMULA: C₁₉₄H₃₃₉N₆₃O₅₄S₁

MOLECULAR WEIGHT: 4450.28

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [398001-88-2]

SYNONYMS:

RESEARCH AREA: Neuropeptides

REFERENCES:
K. Lewis et al., Proc. Natl. Acad. Sci. USA , 98, 7570 (2001)
T. M.Reyes et al., Proc. Natl. Acad. Sci. USA, 98, 2843 (2001)

SKU(s): UROC-003A, UROC-003B

KEYWORDS: