Description

A cyclic peptide that has been discovered to be the endogenous ligand of an orphan GPCR and subsequently has been named the UT receptor. No synthetic ligands are available for investigating this novel peptide-receptor system.

SEQUENCE: H-Glu-Thr-Pro-Asp-Cys-Phe-Trp-Orn-Tyr-Cys-Val-OH (trifluoroacetate salt)
(Cys5 and 10 bridge)

ONE-LETTER SEQUENCE: ETPDCFW-Orn-YCV (Cys5 and 10 bridge)

MOLECULAR FORMULA: C₆₃H₈₃N₁₃O₁₈S₂

MOLECULAR WEIGHT: 1374.5

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [479065-85-5]

SYNONYMS: [Orn8]-Urotensin II (human)

RESEARCH AREA: Cardiovascular

REFERENCES:
Camarda, V., Guerrini, R., Kostenis, E., et al. Br. J. Pharmacol. 137(3), 311-314 (2002).

SKU(s): UROT-004A, UROT-004B

KEYWORDS: