Highlights from NextGen Biomed 2025

March 17, 2025

CPC Scientific had an excellent time returning to NextGen Biomed by Oxford Global 2025, held March 12–14 in London, UK.

We were proud to attend as a Silver Sponsor, joining global experts across the peptide and oligonucleotide therapeutic community in exploring how sustainability and innovation are shaping the next generation of TIDES manufacturing.

Presentation on Sustainable TIDES Manufacturing

On March 13, Joseph Denby (Sr. Manager of Business Development – Europe) delivered a cutting-edge presentation titled “Green Approaches to Peptide API and Peptide–Oligonucleotide Conjugate (POC) Manufacturing.”

Nextgen Biomed 2025 Joseph Denby

Joseph highlighted the critical role of green chemistry in transforming sustainable production of peptide APIs and peptide–oligonucleotide conjugates (POCs).

The talk showcased innovative strategies for minimizing protecting groups and adopting eco-friendly solvents, leading to reduced generation of hazardous waste and improved atom economy across solid-phase peptide synthesis (SPPS) and conjugation.

Case Study: Green Synthesis of Peptide API Impurity

A featured case study in the presentation demonstrated how our team synthesized a Goserelin peptide API impurity, using a convergent fragment-based method. This approach utilized safer solvents and eliminated the need for traditional TFA and diethyl ether cleavage, maintaining purity and yield while lowering environmental impact and material costs.

Our presentation at NextGen Biomed reflects CPC Scientific’s innovation and expertise in applying green chemistry principles that help clients meet sustainable peptide and oligonucleotide manufacturing goals, without compromising quality.

Interested in learning more? Dive into the full details with our white papers below:

  • Green Synthesis of Goserelin Impurity E

    In this case study, we demonstrate the synthesis of a Goserelin peptide API impurity through a convergent peptide fragment strategy, expanding our approach to include the unprotected side chains of histidine, tryptophan, and arginine...

  • minimal protection strategies in SP peptide synthesis

    Solid-phase peptide synthesis approaches require that the side chains of certain amino acids be protected from undesired reactivity during synthesis. The installation and removal of these protection groups results in a lower atom economy…

Looking Ahead to the Future of TIDES Manufacturing

NextGen Biomed 2025 brought together leaders driving greener and more sustainable drug development. We were inspired by the shared focus on sustainable process optimization, regulatory readiness, and the expanding role of CDMOs in enabling compliant and environmentally conscious manufacturing.

As environmental footprint becomes a defining factor in modern drug development, our team continues to drive innovation in GMP peptide and oligonucleotide manufacturing through greener, more cost-efficient practices that can scale. We believe the future of modern chemistry lies in delivering life-changing medicines through methods that are not only efficient but also sustainable.

We’re grateful to everyone who connected with us in London, and we’re looking forward to continuing the conversations and collaborations that have already begun!

Ready to explore sustainable, efficient manufacturing that can scale? Reach out to our team today to discuss how CPC Scientific’s CDMO expertise can meet your peptide and oligonucleotide manufacturing needs.

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