"The tandem peptide library used in this work was synthesized via standard FMOC solid-phase peptide synthesis and purified by high-performance liquid chromatography at the MIT Biopolymers Core, Tufts University Core Facility or CPC Scientific, Inc."
Abstract
Aspects of the invention provide compositions and methods for delivering nucleic acids to target cells.
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Leclair, E., Liggins, R.T., Peckett, A.J., Teich, T., Coy, D.H., Vranic, M. and Riddell, M.C. Diabetologia (2016): 1-8.
"The SSTR2a (PRL-2903) was purchased by CPC Scientific (Sunnyvale, CA, USA) and the dose (10 mg/kg body mass) approximated that given in our prior studies [25–27]. The antagonist was dissolved in saline and given in a 2 ml/kg volume."
April 13th, 2016Citations, Peptide Macrocycles, Showcase Unnatural Amino Acids, Unnatural Amino AcidsHANGZHOU, CHINA – March 17, 2016 – CPC Scientific Inc. is pleased to announce that the CPC Scientific Inc. Good Manufacturing Practice (GMP) facility in Hangzhou, China has successfully passed its fourth U.S. Food and Drug Administration (FDA) inspection. No Form 483 observations were issued.
Passing this inspection is an important milestone for CPC Scientific Inc. […]
March 17th, 2016Press ReleasesPandya, Darpan N., et al. Theranostics 6.5 (2016): 698.
DOTA-c(RGDyK) was purchased from CPC Scientific, Inc. (Sunnyvale, CA), and its purity and mass were confirmed at Wake Forest using HPLC and electrospray ionization (ESI) mass spectrometry as described below.
March 2nd, 2016Citations, Metal Chelates, Peptide Macrocycles, Showcase Peptide ChelatesJiang, Zongrun, et al. Radiochimica Acta 104.7 (2016): 499-512.
"[RGD-Glu-(DO3A)-6-Ahx-RM2], [Cyclo-(Arg-Gly-Asp-D-Tyr- Lys)-(DO3A)-Glu-(6-Ahx-D-Phe-Gln-Trp-Ala-Val-Gly-His- Sta-Leu-NH2)], was purchased from CPC Scientific (Sunnyvale, CA, USA)."
February 26th, 2016Citations, Metal Chelates, Peptide MacrocyclesZhen, Eugene Y., et al. Biochemical Journal (2015): BJ20151085.
- Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN 46285, U.S.A
"Stable isotope-labelled (SIL) peptides were synthesized by CPC Scientific. Leucine residues were selectively labeled using 13C/15N-labelled amino acids resulting in the addition of 7 Da to the peptide mass (Supplementary Table S1). The reported purity of each synthesized peptide was more than 95% based on HPLC analysis. "
February 24th, 2016Citations, Isotope-Labeled PeptidesLopez, A., Reyna, D.E., Gitego, N. et al. Co-targeting of BAX and BCL-XL proteins broadly overcomes resistance to apoptosis in cancer. Nat Commun 13, 1199 (2022).
- Cardio-metabolic Disease Biomarkers, Merck Research Laboratories, Kenilworth, NJ., Merck & Co., Inc.
"Glucagon synthetic peptide and heavy isotope–labeled internal standards (ISs) of oxyntomodulin and glucagon containing 2 [ 13 C 6 - 15 N]-labeled leucines and 1 [ 13 C 9 - 15 N]-labeled phenylalanine were synthesized by CPC Scientific.."
December 10th, 2015Citations, Isotope-Labeled PeptidesDudani, Jaideep S., et al. ACS Nano 9.12 (2015): 11708-11717.
"...protease activity are focused on functionalizing synthetic peptide substrates with reporters that emit ... In vivo, veiled nanosensors are selectively activated at the ..... sized by CPC Scientific, Inc. (V1: Biotin-PEG(5 kDa)-(KFAM)-..."
November 13th, 2015Citations, Dye-Labeled, PEGylationMastren, Tara, et al. Molecular Imaging 14.10 (2015): 11-22.
"Two versions of the peptide L19K were synthesized by CPC Scientific (Sunnyvale, CA) consisting of the sequence DO3A- or NO2A-PEG4-GGNECDIARMWEWECFERK-CONH2, with a Cys-Cys disulfide bridge and polyethylene glycol (PEG) as a spacer between peptide and chelate."
October 1st, 2015Citations, Metal Chelates, PEGylationKwong, Gabriel A., et al. Proceedings of the National Academy of Sciences 112.41 (2015): 12627-12632.
"Cysteine-terminated peptides (Q1 = 5FAM-GGPLGVRGKK(CPQ-2)-PEG2-C, CPC Scientific.."
September 28th, 2015Citations, Dye-Labeled, FRET Substrates, PEGylation


